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Abacavir (ABC) is super potent reverse transcriptase inhibitor, meant for the coarse of action of AIDS. ABC is capable of crossing a blood-brain barrier. It has been swell tolerated; independent side consequence existence hypersensitivity reactions, which can be unsafe.
Tries that come insubordinate to AZT or 3TC come generally sensitive to abacavir, whereas tries that are immune to AZT & 3TC are non when sensitive to abacavir. Abacavir is given orally & has the high bio-availability of 83 %. These are metabolised primarily across alcohol dehydrogenase or gluconyl transferase.
This drug is available under a brand name Ziagen (GlaxoSmithKline) and within the combination drug Trizivir (GlaxoSmithKline).
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Abacavir
Antiretroviral, reverse transcriptase inhibitor.
Ziagen
Product information for US residents in PDF format. [Acrobat Reader required]
MedlinePlus: Abacavir and Lamivudine (Systemic)
Features information about dosage, usage, warnings, and side effects.
DrugDigest: Abacavir ( Ziagen )
Information on dosage, usage, side effects, interactions, and drug comparisons including generics when available.
Abacavir, Zidovudine, and Lamivudine - AidsMeds.com
Consumer information on Trizivir with links to forums, general AIDS topics, and other resources for AIDS patients.
MedlinePlus: Abacavir
Features information about dosage, usage, warnings, and side effects.
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